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Angiogenesis in Lung Cancer
Lung cancer, like most other solid tumors, relies on the growth of new blood vessels, called angiogenesis, to provide a steady supply of oxygen and nutrients. As they grow, tumors pump out large quantities of proteins called growth factors that stimulate angiogenesis. The best-studied angiogenesis-stimulating factor is vascular endothelial growth factor (VEGF). Tumors that produce copious amounts of VEGF are faster growing, more aggressive, and more prone to spread (metastasize) to other organs of the body.


Last updated July 15, 2011